AFOB Newsletter

vol.24
April 15, 2024

My Lab

Prof. Mashkoor Mohsin

24_lab_01.jpg

24_lab_02.jpg Mashkoor Mohsin, Ph.D.
Associate Professor
Institute of Microbiology
University of Agriculture Faisalabad, Faisalabad, Pakistan
E-mail: mashkoormohsin@uaf.edu.pk
























https://www.uaf.edu.pk/EmployeeDetail.aspx?userid=809

My name is Mashkoor Mohsin, and I currently hold the position of Associate Professor in Microbiology at the University of Agriculture Faisalabad, Pakistan. I completed my veterinary medicine degree in 2003 from the University of Agriculture Faisalabad and obtained my Ph.D. in 2010 from Quaid-i-Azam University, Islamabad, Pakistan. Following that, I was honored with the Alexander von Humboldt Postdoc Fellowship, Germany, during 2010-2012, where I conducted research at Freie University Berlin under the guidance of Prof. Lothar H. Wieler. Additionally, I received the Matsumae International Foundation Postdoc Fellowship at Gifu University, Japan, in 2019, and I served as a Visiting Research Fellow under the GCRF fellowship at Cardiff University, UK.

My primary research interest lies in antimicrobial resistance (AMR), which poses a significant global challenge and hinders the achievement of various sustainable development goals. The impact of AMR is severe, with 4.95 million deaths reported globally in 2019, particularly affecting South Asian countries with a high burden of drug-resistant infections. In my laboratory, we investigate the genomic epidemiology of multidrug-resistant Gram-negative bacteria at the interface of human-animal-environment, employing a One-Health approach. Specifically, I focus on understanding the spread and transmission of emerging plasmid-mediated resistance to colistin, carbapenem, and tigecycline, which has arisen due to extensive antimicrobial usage. I am also engaged in longitudinal monitoring of antimicrobial usage and resistance in broiler farms to elucidate the relationship between resistance emergence and antimicrobial use, as well as studying the horizontal spread of AMR within the broiler production pyramid, from farm to fork. My contributions to scientific literature include over 75 articles published in peer-reviewed journals, with approximately 32 of them authored as corresponding author, appearing in prestigious journals such as The Lancet Microbes and Nature Communication.

Furthermore, I have served on various national and international advisory committees and technical groups, including being a member of the Quadripartite Technical Group on Antimicrobial Resistance and Use Integrated Surveillance by the World Health Organization (WHO). Currently, I am honored to hold the position of Regional Resource Person on Antimicrobial Usage and Antimicrobial Resistance for Asia and the Pacific, designated by the World Organization for Animal Health (WOAH). Additionally, I have contributed to the Fleming Fund (UKAid Program) as an advisor for the surveillance of antimicrobial usage in food animals in Pakistan. In this capacity, I have conducted pivotal national point prevalence surveys on antimicrobial usage in the dairy and poultry sectors. I frequently provide scientific advice to government ministers, aiding in setting priorities for AMR and antimicrobial usage surveillance in food animals and facilitating evidence gathering efforts.

I anticipate conducting a study utilizing metagenomics to explore the evolution of gut microbiome and resistome throughout the life stages of broiler chickens. Furthermore, I am enthusiastic about addressing the antimicrobial resistance (AMR) crisis through the implementation of interventions such as phytobiotics, probiotics, and prebiotics as alternatives to antimicrobials in the poultry sector, aiming to mitigate both AMR and antimicrobial usage (AMU). Embracing a "One Health" approach encompassing human, animal, plant, and environmental health is crucial in our collective efforts to combat AMR.